Generic Abilify ( Aripiprazole )
Abilify
Abilify is an antipsychotic drug to relieve symptoms of schizophrenia and bipolar disorder.
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Abilify
5 mg
-
30 Comp.
Kč1142.35
Kč 952.03
Kč 31.79 por pílula
salvar:  Kč0.00
Abilify
5 mg
-
60 Comp.
Kč1508.45
Kč 1257.04
Kč 20.99 por pílula
salvar:  Kč648.26
Abilify
5 mg
-
90 Comp.
Kč1954.54
Kč 1628.75
Kč 18.08 por pílula
salvar:  Kč1234.18
Abilify
5 mg
-
120 Comp.
Kč2194.52
Kč 1828.84
Kč 15.17 por pílula
salvar:  Kč1994.64
Abilify
5 mg
-
180 Comp.
Kč2743.67
Kč 2286.36
Kč 12.67 por pílula
salvar:  Kč3440.75
Abilify
10 mg
-
30 Comp.
Kč1439.88
Kč 1199.90
Kč 40.10 por pílula
salvar:  Kč0.00
Abilify
10 mg
-
60 Comp.
Kč1911.53
Kč 1599.66
Kč 26.60 por pílula
salvar:  Kč810.32
Abilify
10 mg
-
120 Comp.
Kč2286.15
Kč 1905.09
Kč 15.79 por pílula
salvar:  Kč2917.16
Abilify
10 mg
-
90 Comp.
Kč2285.53
Kč 1911.32
Kč 21.19 por pílula
salvar:  Kč1701.68
Abilify
10 mg
-
180 Comp.
Kč2858.15
Kč 2381.72
Kč 13.30 por pílula
salvar:  Kč4824.54
Abilify
15 mg
-
30 Comp.
Kč1321.24
Kč 1101.00
Kč 36.78 por pílula
salvar:  Kč0.00
Abilify
15 mg
-
60 Comp.
Kč2119.10
Kč 1765.88
Kč 29.50 por pílula
salvar:  Kč436.33
Abilify
15 mg
-
120 Comp.
Kč2642.69
Kč 2202.21
Kč 18.28 por pílula
salvar:  Kč2219.04
Abilify
15 mg
-
90 Comp.
Kč2966.82
Kč 2472.31
Kč 27.43 por pílula
salvar:  Kč841.49
Abilify
15 mg
-
180 Comp.
Kč3201.19
Kč 2667.62
Kč 14.75 por pílula
salvar:  Kč3964.35
Abilify
20 mg
-
30 Comp.
Kč2193.90
Kč 1828.21
Kč 60.88 por pílula
salvar:  Kč0.00
Abilify
20 mg
-
60 Comp.
Kč3714.81
Kč 3095.64
Kč 51.53 por pílula
salvar:  Kč560.99
Abilify
20 mg
-
90 Comp.
Kč5086.12
Kč 4238.40
Kč 47.16 por pílula
salvar:  Kč1234.18
Abilify
20 mg
-
120 Comp.
Kč6781.57
Kč 5651.27
Kč 47.16 por pílula
salvar:  Kč1645.58
Abilify
20 mg
-
180 Comp.
Kč9150.20
Kč 7625.13
Kč 42.39 por pílula
salvar:  Kč3328.56
Abilify
30 mg
-
30 Comp.
Kč1828.84
Kč 1524.03
Kč 50.70 por pílula
salvar:  Kč0.00
Abilify
30 mg
-
60 Comp.
Kč3292.61
Kč 2743.88
Kč 45.71 por pílula
salvar:  Kč299.20
Abilify
30 mg
-
90 Comp.
Kč4527.83
Kč 3773.19
Kč 41.97 por pílula
salvar:  Kč785.39
Abilify
30 mg
-
120 Comp.
Kč5763.06
Kč 4802.51
Kč 40.10 por pílula
salvar:  Kč1271.58
Abilify
30 mg
-
180 Comp.
Kč8233.29
Kč 6861.15
Kč 38.02 por pílula
salvar:  Kč2281.37
Common use

Abilify is an add-on medication used for the treatment of major depressive disorder, schizophrenia, manic and mixed episodes associated with bipolar disorder in adults and children and adolescents and also of irritability associated with autistic disorder in pediatric patients. The mechanism of action of Abilify is unknown. It shows partial agonism at the D2 receptor, it is also a partial agonist at the 5-HT1A receptor, and also displays an antagonist profile at the 5-HT2A receptor. It has moderate affinity for histamine and alpha adrenergic receptors, and no appreciable affinity for cholinergic muscarinic receptors.



Dosage and direction

Take Abilify once a daily with or without food. The usual starting dose is 10 or 15 mg, later the dose may be increased to achieve the desired effect.



Precautions



This medication was not approved for use in elderly people with psychosis related to dementia-related psychosis due to the risk of death. Antidepressants increase suicidal thoughts or behaviors in some adolescents especially if the dose is changed or during first period of treatment. Abilify was not approved for use in pediatric patients with depression. As Abilify is able impair judgment, thinking, or motor skills do not use is during operating hazardous machinery, including automobiles if you are not sure that Abilify therapy does not affect you adversely. Inform your doctor if you are pregnant, plan to become pregnant or breastfeeding before to take this medication. Avoid drinking any alcoholic beverages during treatment. Avoid overheating and dehydration. Hyperglycemia, or elevated blood sugar, may occur when taking Abilify. If you have diabetes mellitus, monitor your blood sugar levels regularly.



Contraindications

Breastfeeding, hypersensitivity.



Possible side effect

Most common adverse effects include nausea, vomiting, constipation, headache, dizziness, nervousness, sleeplessness, restlessness, tremors, cough, headache, insomnia, lightheadedness, rash, runny nose, weakness, and weight gain. More serious and rare adverse reactions such as an increased risk of stroke and ministroke; neuroleptic malignant syndrome (NMS) which symptoms include fever, rigid muscles, confusion; tardive dyskinesia (TD) which symptoms include uncontrolled and abnormal movements of body parts.



Drug interaction

Inform your doctor about all prescribed and over-the-counter medications and herbal products you are taking and especially if you use alcohol, blood pressure drugs, carbamazepine, fluoxetine, ketoconazole, paroxetine, and quinidine.

Carbamazepine (Tegretol) decreases the levels of Abilifyole in the body stimulating the liver enzymes such as CYP3A4. Similar influence on Abilify is shown by phenytoin (Dilantin), rifampin (Rifadin, Rimactane, Rifadin, Rifater, Rifamate), and phenobarbital. Blocking of CYP3A4 by Ketoconazole (Nizoral) increases the amount of Abilify in the body. Other drugs with similar action are: itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), cimetidine (Tagamet), verapamil (Calan, Isoptin), diltiazem (Cardizem, Dilacor), erythromycin, clarithromycin (Biaxin), nefazodone (Serzone), ritonavir (Norvir), saquinavir (Invirase), nelfinavir (Viracept), indinavir (Crixivan), and grapefruit juice. Their action is not well studied though.

Quinidine (Quinaglute, Quinidex) inhibits another liver enzyme known as CYP2D6 and also is able to increase the levels of Abilify. Other medicines with similar action are fluoxetine (Prozac) and paroxetine (Paxil). Abilify may dangerously increase blood sugar levels in patients with diabetes.





Missed dose

Abilify is taken once daily, so take the missed dose as soon as you remember. If the next dose is within 12 hours, do not take the missed dose and resume your normal dosing schedule. Never double the dose this medication.



Overdose

Common adverse reactions include vomiting, somnolence, and tremor. Other clinically important signs and symptoms observed iare acidosis, aggression, aspartate aminotransferase increased, atrial fibrillation, bradycardia, coma, confusional state, convulsion, blood creatine phosphokinase increased, depressed level of consciousness, hypertension, hypokalemia, hypotension, lethargy, loss of consciousness, QRS complex prolonged, QT prolonged, pneumonia aspiration, respiratory arrest, status epilepticus, and tachycardia.



Storage

Store at room temperature in a tight dry container out of reach of children and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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